MYELODYSPLASTIC SYNDROME

CAT.# FP-018: CHROMOSOME 8 PROBE

IVD/RUO

BACKGROUND

Trisomy 8 is the most common cytogenetic abnormality detected in MDS patients in China and Southeast Asia occurring between 25-31% of MDS patients.

PROBE DESCRIPTION

The centromere region of chromosome 8 is directly labeled with an orange-red fluorescent dye.

CLINICAL SIGNIFICANCE 

Immunosuppressive therapy is effective in MDS patients with simple +8, with poor prognosis.

CEP8 [--]
CEP8 [+]

     References

  • Kawankar N, et al. (2010) Hematology, 16:131-8. 
  • Coleman JF, et al. (2011) Am J Clin Pathol 135: 915-20.
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